Annual Congress Amsterdam 2011

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Adenosine and purigenic signalling in inflammatory lung disease

Symposium
Chairs: J. C. Virchow (Rostock, Germany), C. Page (London, United Kingdom)
Aims: At the end of the session the audience will understand:
- that endogenously released ATP and adenosine are important regulators of the immune system;
- the complexity of P2 and adenosine receptor signalling in lung physiology;
- that specific P2R/adenosine receptor subtypes play a key role in the pathogenesis of inflammatory lung diseases;
- that ATP contributes to chronicity of inflammatory lung diseases and airway remodelling;
- that targetting specific P2R/adenosine receptors is a new therapeutic approach for the treatment of chronic
inflammatory lung diseases, such as COPD, lung fibrosis and severe asthma.

Introductory talk: pharmacology of adenosine and purinergic signalling G. Folkerts (Utrecht, The Netherlands)
Adenosine signalling in asthma and COPD R. Polosa (Catania, Italy)