S. Tas (Lund, Sweden), D. Tschumperlin (Rochester, United States of America)
Late Breaking Abstract - 3D Bioprinting of Decellularised Porcine Lung ECM
S. Tas (Lund, Sweden), D. Bölükbas (Lund, Sweden), H. Alsafadi (Lund, Sweden), M. De Santis (Lund, Sweden), D. Wagner (Lund, Sweden)
|   |
SH2 domain-containing Phosphatase-(SHP)-2 blunts fibrotic responses through regulation of fibroblast mitochondrial metabolism and autophagy
A. Tzouvelekis (Athens, Greece), G. Yu (New Haven, CT, United States of America), F. Ahangari (New Haven, CT, United States of America), A. Bennett (New Haven, CT, Greece), T. Karampitsakos (Athens, Greece), D. Bouros (Athens, Greece), E. Bouros (Athens, Greece), N. Kaminski (New Haven, CT, United States of America)
| |
Alterations in mitochondrial permeability transition pore contribute to apoptosis resistance in IPF fibroblasts.
A. Pardo Semo (Mexico City, Mexico), E. Luis-Garcia (Mexico City, Mexico), C. Becerril (Mexico City, Mexico), C. Mendoza (Mexico City, Mexico), M. Maldonado (Mexico City, Mexico), E. Aparicio Trejo (Mexico City, Mexico), M. Selman (Mexico City, Mexico)
| |
Human lung stiffness and viscoelasticity replicated in extracellular matrix hydrogels
R. de Hilster (Groningen, Netherlands), M. Jonker (Groningen, Netherlands), W. Timens (Groningen, Netherlands), P. Sharma (Groningen, Netherlands), M. Harmsen (Groningen, Netherlands), M. Hylkema (Groningen, Netherlands), J. Burgess (Groningen, Netherlands)
| |
Stiffness and viscoelasticity of human lung tissue unaltered by freeze-thawing
R. de Hilster (Groningen, Netherlands), M. Jonker (Groningen, Netherlands), W. Timens (Groningen, Netherlands), P. Sharma (Groningen, Netherlands), M. Harmsen (Groningen, Netherlands), J. Burgess (Groningen, Netherlands), M. Hylkema (Groningen, Netherlands)
| |
Engineering distal pulmonary epithelium from induced pluripotent stem cell (iPSC)-derived alveolar cells
S. Gilpin (Boston, United States of America), T. Wu (Boston, United States of America), D. Gorman (Boston, United States of America), L. Zhu (Boston, United States of America), D. Evangelista-Leite (Boston, United States of America), M. Vedaie (Boston, United States of America), D. Kotton (Boston, United States of America), H. Ott (Boston, United States of America)
| |
Increased susceptibility to gammaherpesvirus-induced lung fibrosis of transgenic mice with conditional overexpression of the ER-stress-factor Chop in alveolar epithelium
M. Korfei (Giessen, Germany), M. Smaida (Giessen, Germany), O. Klymenko (Giessen, Germany), C. Ruppert (Giessen, Germany), I. Henneke (Giessen, Germany), I. Shalashova (Giessen, Germany), M. Huehn (Giessen, Germany), P. Mahavadi (Giessen, Germany), S. Herold (Giessen, Germany), W. Seeger (Giessen, Germany), H. Adler (Munich, Germany), A. Guenther (Giessen, Germany)
| |
Preclinical data using a novel porcupine inhibitor demonstrates that inhibition of porcupine is a promising target for the treatment of Idiopathic Pulmonary Fibrosis.
P. Bunyard (Alderley Edge, United Kingdom), I. Bhamra (Alderley Edge, United Kingdom), K. Eckersley (Alderley Edge, United Kingdom), C. Chaplin (Alderley Edge, United Kingdom), N. Guisot (Alderley Edge, United Kingdom), C. Jones (Alderley Edge, United Kingdom), C. Phillips (Alderley Edge, United Kingdom), R. Armer (Alderley Edge, United Kingdom)
| |
In vitro modelling of epithelia-fibroblast interactions in idiopathic pulmonary fibrosis
H. Le (Biberach an der Riss, Germany), V. Schroeder (Biberach an der Riss, Germany), J. Schütt (Biberach an der Riss, Germany), J. Wirth (Biberach an der Riss, Germany), A. Campos (La Jolla, United States of America), J. Li (Ridgefield, United States of America), M. Thomas (Biberach an der Riss, Germany), F. Herrmann (Biberach an der Riss, Germany), J. Garnett (Biberach an der Riss, Germany)
| |
TGFß1 induces collagen deposition and increased tissue stiffness in sarcoidosis fibroblasts grown in a novel, long term, 3D culture system.
M. Ward (Dublin, Ireland), D. Smart (Southampton, United Kingdom), J. Roberts (Southampton, United Kingdom), P. Monk (Southampton, United Kingdom), J. Baugh (Dublin, Ireland), M. Jones (Southampton, United Kingdom), D. Davies (Southampton, United Kingdom), K. O'Reilly (Dublin, Ireland)
| |
Anti-fibrotic drugs differently affect inflammatory and redox status in bronchial epithelial cells from Idiopathic Pulmonary Fibrosis patients
A. Boots (Maastricht, Netherlands), C. Veith (Maastricht, Netherlands), M. Kreuter (Heidelberg, Germany), M. Schneider (Heidelberg, Germany), M. Meister (Heidelberg, Germany), F. Van Schooten (Maastricht, Netherlands), N. Kahn (Heidelberg, Germany)
| |
PAR-2 antagonist inhibits bleomycin-induced lung fibrosis.
T. Suzuki (Aizuwakamatsu, Japan), X. Wang (Fukushima, Japan), T. Nikaido (Fukushima, Japan), Y. Tanino (Fukushima, Japan), M. Saitou (Aizuwakamatsu, Japan), M. Munakata (Aizuwakamatsu, Japan), Y. Shibata (Fukushima, Japan), K. Niitsuma (Aizuwakamatsu, Japan)
| |
Inhibition of the Arp2/3 complex inhibits lung myofibroblast differentiation in vitro and attenuates bleomycin-induced pulmonary fibrosis in mice
C. Mergault (Tours, France), F. Lisée (Tours, France), V. Tiroille (Tours, France), N. Heuzé-Vourc'H (Tours, France), C. Parent (Tours, France), D. Sizaret (Tours, France), S. Marchand-Adam (Tours, France), L. Plantier (Tours, France)
| |
PGAM5 acts as a key mediator of lung fibrosis by disrupting mitochondrial homeostasis
I. Ganzleben (Erlangen, Germany), G. He (Erlangen, Germany), C. Günther (Erlangen, Germany), E. Prigge (Heidelberg, Germany), K. Richter (Heidelberg, Germany), R. Rieker (Erlangen, Germany), D. Mougiakakos (Erlangen, Germany), M. Neurath (Erlangen, Germany), C. Becker (Erlangen, Germany)
| |
Alveolar epithelial wound repair is delayed by scenescent lung fibroblasts in IPF
K. Blokland (Groningen, Netherlands), D. Waters (Callaghan, Australia), M. Schuliga (Callaghan, Australia), S. Pouwels (Groningen, Netherlands), C. Grainge (Callaghan, Australia), S. Mutsaers (Crawley, Australia), C. Prêle (Crawley, Australia), G. Westall (Prahran, Australia), J. Jaffar (Prahran, Australia), D. Knight (Callaghan, Australia), J. Burgess (Groningen, Netherlands)
| |
The Transciptome of BAL Cells at Acute Exacerbation of IPF reveals New Insights.
A. Carleo (Hannover, Germany), D. Deluca (Hannover, Germany), E. Bargagli (Siena, Italy), W. Wuyts (Leuven, Belgium), N. Kaminski (Leuven, Belgium), A. Prasse (Hannover, Germany)
| |
Precision cut lung slices from bleomycin challenged mice – ex vivo model for testing novel therapies for lung fibrosis
M. Cedilak (Zagreb, Croatia), M. Banjanac (Zagreb, Croatia), D. Belamaric (Zagreb, Croatia), I. Faraho (Zagreb, Croatia), I. Glojnaric (Zagreb, Croatia), V. Erakovic Haber (Zagreb, Croatia), M. Bosnar (Zagreb, Croatia)
| |
CHARACTERIZATION OF ACELLULAR LUNG SCAFFOLDS DERIVED FROM EQUINE ASTHMA MODEL
R. Palma (BARCELONA, Spain), A. Cereta (SAO PAULO, Brazil), L. Guimaraes (SAO PAULO, Brazil), A. De Almeida Da Anunciação (SAO PAULO, Brazil), A. Delgado (SAO PAULO, Brazil), J. Conceição Da Silva Paulino (SAO PAULO, Brazil), L. Oliveira (Anapolis, Brazil), M. Miglino (SAO PAULO, Brazil)
| |