Research Seminars

About

Research Seminars gather a small number (20 to 100) of well-established and preferably young investigators to address scientific topics in depth and help break new ground. Research Seminars take place over two days in easy-to-reach European cities. They are scientific Seminars involving recently published work and research in progress. Participation is fully supported by the budget granted by the ERS.



Translational animal models of asthma

Animal models of asthma have proven to be very valuable for dissecting the cellular and molecular mechanisms and to explore novel therapeutic opportunities. However, our knowledge of the risk factors and the pathogenesis of asthma is continually evolving. Animal models of asthma have focused on Th2-driven disease manifestations although these models are not sufficient to cover the complexity of asthma (sub)phenotypes. Little attention is paid to the modeling of symptoms such as cough, dyspnea, bronchospasm with most of the focus being on inflammatory endpoints. Therefore, novel and improved translational models are needed. This Research Seminar aims to discuss the strengths and weaknesses of current animal models and compare these with clinical translational endpoints.
Asthma
S. Holgate (Southampton, United Kingdom)
PDF journal article, handout or slidesSlide presentation
PDF journal article, handout or slidesSlide presentation
European Asthma Research and Innovation Partnership (EARIP)
S. Walker (London, United Kingdom)
PDF journal article, handout or slidesSlide presentation
PDF journal article, handout or slidesSlide presentation
Collaborative Partnerships: a new model for drug discovery
I. Anderson (London, United Kingdom)
No content made available
No content made available
Modeling asthma subphenotypes, what is missing?
L. Heaney (Belfast, United Kingdom)
No content made available
No content made available
Asthma Clinical Trials: Biomarker Discovery
J. Matthews (San Francisco, Ca, United States of America)
No content made available
No content made available
Classic and improved animal models of asthma
A. Van Oosterhout (Groningen, Netherlands)
No content made available
No content made available
Airway hyperreactivity and remodeling in asthma
S. Siddiqui (Leicester, United Kingdom)
No content made available
No content made available
Airway hyperreactivity in animal models
A. Braun (Hannover, Germany)
PDF journal article, handout or slidesSlide presentation
PDF journal article, handout or slidesSlide presentation
Assessment of symptoms: Cough reflex and LAR
M. Belvisi (London, United Kingdom)
PDF journal article, handout or slidesSlide presentation
PDF journal article, handout or slidesSlide presentation
Airway remodeling in mouse models
C. Lloyd (London, United Kingdom)
PDF journal article, handout or slidesSlide presentation
PDF journal article, handout or slidesSlide presentation
Are Murine Models of Asthma enough
C. Page (London, United Kingdom)
PDF journal article, handout or slidesSlide presentation
PDF journal article, handout or slidesSlide presentation
PAMPs and DAMPs in Allergy: Exacerbation Models
M. Kool (Rotterdam, Netherlands)
PDF journal article, handout or slidesSlide presentation
PDF journal article, handout or slidesSlide presentation
The microbiology of asthma
S.L. Johnston (London, United Kingdom)
PDF journal article, handout or slidesSlide presentation
PDF journal article, handout or slidesSlide presentation