Therapeutic horizons: novel targets and pharmacological models

Oral Presentation
Chairs: Ross Vlahos (Bundoora, Australia), Hoeke Baarsma (Munich, Germany)
LATE-BREAKING ABSTRACT: MUC1 downregulation induces corticosteroid resistance in asthma’s in vitro and in vivo models
Anselm Morell (Valencia, Spain), Anselm Morell, Estefania Bel, Javier Milara, Esteban Morcillo, Julio Cortijo
Congress or journal article abstract
Congress or journal article abstract
Intratracheal administration of bone marrow-derived mesenchymal stem cells ameliorates lung function
Giuseppe Spaziano (Naples, Italy), Giuseppe Spaziano, Konrad Urbanek, Antonella De Angelis, Elena Piegari, Maria Matteis, Manuela Sgambato, Gioia Tartaglione, Teresa Palmira Russo, Donato Cappetta, Grazia Esposito, Rosa Russo, Bruno D’Agostino
Congress or journal article abstractSlide presentation
Congress or journal article abstractSlide presentation
Pharmacological characterization of CHI25243, a novel potent inhaled inhibitor of neutrophil elastase
Daniela Miglietta (Parma, Italy), Daniela Miglietta, Chiara Carnini, Veronica Puviani, Harry Finch, Craig Fox, Mary Fitzgerald, Riccardo Patacchini, Maurizio Civelli, Gino Villetti
Congress or journal article abstractSlide presentationE-poster
Congress or journal article abstractSlide presentationE-poster
Strong reversal of the lung fibrosis disease signature by autotaxin inhibitor GLPG1690 in a mouse model for IPF
Maté Ongenaert (Mechelen, Belgium), Maté Ongenaert, Sonia Dupont, Roland Blanqué, Reginald Brys, Ellen van der Aar, Bertrand Heckmann
Congress or journal article abstractSlide presentationE-poster
Congress or journal article abstractSlide presentationE-poster
The anti-inflammatory effects of eucalyptol in a mouse model of LPS-induced pulmonary inflammation are mediated by TRPM8
Ana Isabel Caceres (Durham, United States of America), Anabel de Caceres Bustos, Boyi Liu, Sairam Jabba, John Morris, Sven-Eric Jordt
Congress or journal article abstract
Congress or journal article abstract
Human small airway-on-a-chip: A novel microphysiological system to model lung inflammation, accelerate drug development and enable inhalational toxico-analysis
Kambez Hajipouran Benam (Cambridge, United States of America), Kambez Hajipouran Benam, Richard Novak, Remi Villenave, Carolina Lucchesi, Cedric Hubeau, Janna Nawroth, Mariko Hirano-Kobayashi, Thomas C. Ferrante, Youngjae Choe, Rachelle Prantil-Baun, James C. Weaver, Geraldine A. Hamilton, Anthony Bahinski, Donald E. Ingber
Congress or journal article abstract
Congress or journal article abstract
Evaluation of nanoparticles in human lung fibroblasts and PCLS
Anna-Karin Larsson-Callerfelt (Lund, Sweden), Gunilla Westergren-Thorsson, Lena Thiman, Vendela Rissler, Hanna Karlsson, Anna-Karin Larsson-Callerfelt
Congress or journal article abstract
Congress or journal article abstract
Ex vivo elastase and hydrogen peroxide stimulation in lung slices: novel models to study lung repair
Loes Kistemaker (Groningen, Netherlands), Loes E.M. Kistemaker, Eline M. van Dijk, Sule Culha, John-Poul Ng-Blichfeldt, Mark H. Menzen, Reinoud Gosens
Congress or journal article abstractSlide presentation
Congress or journal article abstractSlide presentation