P. Bhavsar (London, United Kingdom), C. Page (London, United Kingdom)
Late Breaking Abstract - Sex differences in ß2 adrenoceptor-mediated responses in mouse airways I. Cerqua (Naples, Italy), A. Rossi (Naples, Italy), M. Riemma (Naples, Italy), G. Cirino (Naples, Italy), F. Roviezzo (Naples, Italy)
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Pharmacological characterization of the protective effect of benralizumab against airway hyperresponsiveness in a human ex vivo model of severe asthma P. Rogliani (Rome, Italy), M. Matera (Naples, Italy), F. Cavalli (Rome, Italy), F. Facciolo (Rome, Italy), M. Cazzola (Rome, Italy), L. Calzetta (Rome, Italy)
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Generation and activation of myeloid derived suppressor cells using prostaglandin E2 and EP receptor agonists in vitro C. Van Geffen (Tübingen, Germany), S. Beer-Hammera (Tübingen, Germany), B. Nürnberg (Tübingen, Germany), S. Kolahian (Tübingen, Germany)
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In vitro pharmacological characterization of the potent, lung selective pan-JAK inhibitor TD-8236 R. Sana (South San Francisco, United States of America), W. Krey-Epstein (South San Francisco, United States of America), E. Sandvik (South San Francisco, United States of America), E. Gordon (South San Francisco, United States of America), S. Calhoun (South San Francisco, United States of America), E. Kaufman (South San Francisco, United States of America), J. Budman (South San Francisco, United States of America), P. Fatheree (South San Francisco, United States of America), M. Kleinschek (South San Francisco, United States of America)
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Mechanisms leading to the bronchorelaxant synergy of ICS/LABA/LAMA combination L. Calzetta (Rome, Italy), M. Matera (Naples, Italy), J. Ora (Rome, Italy), F. Facciolo (Rome, Italy), M. Cazzola (Rome, Italy), P. Rogliani (Rome, Italy)
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Pharmacological characterization of the protective effect of mepolizumab against airway hyperresponsiveness in a human ex vivo model of severe asthma L. Calzetta (Rome, Italy), M. Matera (Naples, Italy), F. Cavalli (Rome, Italy), F. Facciolo (Rome, Italy), M. Cazzola (Rome, Italy), P. Rogliani (Rome, Italy)
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Investigating Transient Receptor Potential V4 channel induced bronchospasm P. Flajolet (London, United Kingdom), S. Bonvini (London, United Kingdom), B. Dekkak (London, United Kingdom), N. Kobold (London, United Kingdom), J. Adcock (Gothenburg, Sweden), P. Bradding (Leicester, United Kingdom), M. Belvisi (Gothenburg, Sweden), M. Birrell (Gothenburg, Sweden)
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IL-33 blockade prevents exacerbations in a model of chronic airway inflammation by blunting persistent inflammation and remodeling J. Allinne (Tarrytown, United States of America), W. Lim (Tarrytown, United States of America), G. Scott (Tarrytown, United States of America), C. Sandén (Lund, Sweden), J. Erjefält (Lund, Sweden), D. Birchard (Tarrytown, United States of America), L. Ben (Tarrytown, United States of America), A. Murphy (Tarrytown, United States of America), M. Sleeman (Tarrytown, United States of America), J. Orengo (Tarrytown, United States of America)
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Broader Impact of IL-4Ra Blockade Than IL-5 Blockade on Type 2 Inflammation J. Allinne (Tarrytown, United States of America), G. Scott (Tarrytown, United States of America), D. Birchard (Tarrytown, United States of America), S. Asrat (Tarrytown, United States of America), K. Nagashima (Tarrytown, United States of America), A. Le Floc'H (Tarrytown, United States of America), M. Sleeman (Tarrytown, United States of America), A. Murphy (Tarrytown, United States of America), G. Yancopoulos (Tarrytown, United States of America), J. Orengo (Tarrytown, United States of America)
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The effect of endocannabinoid metabolism inhibition on airway inflammation in mice R. Abohalaka (Ankara, Turkey), T. Bozkurt (Ankara, Turkey), E. Nemutlu (Ankara, Turkey), S. Onder (Ankara, Turkey), I. Sahin-Erdemli (Ankara, Turkey)
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Intranasal treatment with the mitochondria-targeted slow hydrogen sulfide releasing donor AP39 prevents inflammation-induced airway hyperreactivity in mice Y. Karaman-Kutluay (Ankara, Turkey), Y. Kaya-Yasar (Trabzon, Turkey), T. Bozkurt (Ankara, Turkey), S. Celik Onder (Ankara, Turkey), I. Sahin-Erdemli (Ankara, Turkey)
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Relaxin potentiates ß2-adrenoceptor mediated bronchodilation in precision-cut lung slices (PCLS) from mouse models of airway inflammation and fibrosis, and in human airways J. Bourke (Clayton, Australia), M. Lam (Clayton, Australia), C. Maksdi (Clayton, Australia), J. Chitty (Clayton, Australia), B. Thomas (Clayton, Australia), P. Bardin (Clayton, Australia), J. Jaffar (Prahran, Australia), G. Westall (Prahran, Australia), S. Royce (Clayton, Australia)
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Bronchial thermoplasty induces cell type specific anti-airway remodeling via secreted HSP in vitro L. Fang (Basel, Switzerland), M. Tamm (Basel, Switzerland), M. Roth (Basel, Switzerland), D. Stolz (Basel, Switzerland)
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TLR7 Expression Reveals Novel Bronchodilating Mechanism of Imidazoquinoline Agonists B. Proskocil (Portland, United States of America), A. Fryer (Portland, United States of America), D. Jacoby (Portland, United States of America), M. Drake (Portland, United States of America)
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The calcium-sensing receptor CaSR mediates airway contraction in a house dust mite model of allergic airway disease J. Bourke (Clayton, Australia), J. Diao (Parkville, Australia), M. Lam (Clayton, Australia), C. Maksdi (Clayton, Australia), K. Gregory (Parkville, Australia), K. Leach (Parkville, Australia)
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The sensory irritant receptor TRPA1 is essential for airway inflammation in the LPS mouse model of acute lung injury. A. Caceres (Durham, NC , United States of America), S. Jordt (Durham, NC , United States of America)
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