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Tuberculosis

European Respiratory Society Monograph, Vol. 82. 2018
ISBN (electronic): 978-1-84984-100-9
10.1183/2312508X.erm8218

With over 10 million new TB cases and 1.6 million deaths, TB is a global health priority. Multidrug-resistant TB is of particular concern to both clinicians and national TB programmes: in 2017, there were 558 000 new rifampicin-resistant cases and 460 000 confirmed multidrug-resistant TB cases. Despite extensive investigation over the years, there is still a great deal to learn about the prevention, diagnosis and treatment of TB. This Monograph brings together chapters from global TB experts and begins with a patients' perspective that sets the tone. The following chapters cover: the history of TB; epidemiology; strategies for control and elimination; clinical and laboratory diagnosis; imaging; treatment and drugs; TB in children and different patient populations; comorbidities; clinical cases; and much more.

Preface Robert Bals Eur Respir Monogr 2018; 82: ix
Guest Editors Eur Respir Monogr 2018; 82: x-xiii
Introduction Giovanni Battista Migliori, Graham Bothamley, Raquel Duarte, Adrian Rendon Eur Respir Monogr 2018; 82: xiv-xvi
List of abbreviations Eur Respir Monogr 2018; 82: xvii
The tuberculosis patients’ perspective Gabi Spita, Helen Clegg, Marius Dumitru, Paul Sommerfeld, Courtney Coleman, Pippa Powell Eur Respir Monogr 2018; 82: 1-7
History of tuberculosis Robert Loddenkemper, John F. Murray, Christoph Gradmann, Philip C. Hopewell, Midori Kato-Maeda Eur Respir Monogr 2018; 82: 8-27
Epidemiology and socioeconomic determinants of tuberculosis Raquel Duarte, João V. Santos, André Santos Silva, Giovanni Sotgiu Eur Respir Monogr 2018; 82: 28-35
Evolution of the strategies for control and elimination of tuberculosis Mario C. Raviglione Eur Respir Monogr 2018; 82: 36-61
Aetiopathogenesis, immunology and microbiology of tuberculosis Palmira Barreira-Silva, Egídio Torrado, Hanna Nebenzahl-Guimaraes, Gunilla Kallenius, Margarida Correia-Neves Eur Respir Monogr 2018; 82: 62-82
Clinical diagnosis of tuberculosis Jean-Pierre Zellweger, Pedro Sousa, Jan Heyckendorf Eur Respir Monogr 2018; 82: 83-98
Laboratory diagnosis of tuberculosis Elisa Tagliani, Vlad Nikolayevskyy, Enrico Tortoli, Daniela Maria Cirillo Eur Respir Monogr 2018; 82: 99-115
Imaging for diagnosis and management of tuberculosis Dumitru Chesov, Victor Botnaru Eur Respir Monogr 2018; 82: 116-136
Bronchoscopy and other invasive procedures for tuberculosis diagnosis Angshu Bhowmik, Felix J.F. Herth Eur Respir Monogr 2018; 82: 137-151
Treatment of drug-susceptible and drug-resistant tuberculosis José A. Caminero, Anna Scardigli, Tijp van der Werf, Marina Tadolini Eur Respir Monogr 2018; 82: 152-178
New and repurposed drugs Maria Krutikov, Judith Bruchfeld, Giovanni Battista Migliori, Sergey Borisov, Simon Tiberi Eur Respir Monogr 2018; 82: 179-204
Adverse anti-tuberculosis drug events and their management José A. Caminero, Paula Lasserra, Alberto Piubello, Rupak Singla Eur Respir Monogr 2018; 82: 205-227
Surgery as a treatment for pulmonary tuberculosis Anne Olland, Pierre-Emmanuel Falcoz, Sophie Guinard, Joseph Seitlinger, Gilbert Massard Eur Respir Monogr 2018; 82: 228-233
Challenges in childhood tuberculosis H. Simon Schaaf, Ben J. Marais, Isabel Carvalho, James A. Seddon Eur Respir Monogr 2018; 82: 234-262
Tuberculosis in pregnancy and the elderly Alice Repossi, Graham Bothamley Eur Respir Monogr 2018; 82: 263-275
Tuberculosis and comorbidities Cecile Magis-Escurra, Anna Cristina C. Carvalho, Afrânio L. Kritski, Enrico Girardi Eur Respir Monogr 2018; 82: 276-290
Access and adherence to tuberculosis prevention and care for hard-to-reach groups Kerri Viney, Tom Wingfield, Liga Kuksa, Knut Lönnroth Eur Respir Monogr 2018; 82: 291-307
Monitoring during and after tuberculosis treatment Jan-Willem C. Alffenaar, Onno W. Akkerman, Graham Bothamley Eur Respir Monogr 2018; 82: 308-325
Tuberculosis sequelae assessment and rehabilitation Marcela Muñoz-Torrico, Silvia Cid-Juárez, Susana Galicia-Amor, Thierry Troosters, Antonio Spanevello Eur Respir Monogr 2018; 82: 326-342
Towards a new vaccine for tuberculosis Morten Ruhwald, Peter L. Andersen, Lewis Schrager Eur Respir Monogr 2018; 82: 343-363
Tuberculosis transmission control: a refocused approach Edward Nardell, Grigory Volchenkov Eur Respir Monogr 2018; 82: 364-380
Diagnosis and treatment of latent tuberculosis infection Adrian Rendon, Delia Goletti, Alberto Matteelli Eur Respir Monogr 2018; 82: 381-398
Nontuberculous mycobacteria Sanne Zweijpfenning, Wouter Hoefsloot, Jakko van Ingen Eur Respir Monogr 2018; 82: 399-413
What next? Basic research, new treatments and a patient-centred approach in controlling tuberculosis Graham Bothamley Eur Respir Monogr 2018; 82: 414-429
Opportunities for training and learning in tuberculosis control Caterina Casalini, Alberto Matteelli, Albert Komba, Lia D'Ambrosio, Jan van den Hombergh Eur Respir Monogr 2018; 82: 430-445
Clinical cases Simon Tiberi, Marie Christine Payen, Katerina Manika, Inês Ladeira, Marta Gonzalez Sanz, Marcela Muñoz-Torrico Eur Respir Monogr 2018; 82: 446-460