Airway regenerative medicine: from bench to bedside

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Chairs: H. Heijink (Groningen, Netherlands), I. Adcock (London, United Kingdom)
Aims: to present the tremendous potential of human induced pluripotent stem cells (hiPSCs) for disease modelling and cell therapy development; to discuss research that describes the successful differentiation of hiPSCs into airway epithelium containing multi-ciliated cells, which paves the way for modelling of respiratory diseases in a dish; to present the opportunities offered by this innovative technology to assess the feasibility, efficacy and safety of a wide range of approaches, from gene therapy to ex vivo cell engineering, for transplantation and drug screening; to describe the advantages of hiPSC-derived airway epithelium, which will become essential for the development of new strategies to treat severe chronic airway diseases, in association with gene editing techniques.
Introduction to the mechanisms leading to efficient 2D differentiation of human pluripotent stem cells into functional multi-ciliated airway cells
A. Bourdin (Montpellier Cedex 5, France)
No content made available
No content made available
Derivation of epithelial-only airway organoids from human pluripotent stem cells
H. Snoeck (New York, United States of America)
WebcastSlide presentation
WebcastSlide presentation
Induced pluripotent stem cell-derived alveolar epithelial cells: applications with lung-on-a-chip
T. Geiser (Bern, Switzerland)
WebcastSlide presentation
WebcastSlide presentation
Pulmonary transplantation of human induced pluripotent stem cell-derived macrophages
C. Happle (Hannover, Germany)
WebcastSlide presentation
WebcastSlide presentation