Monograph

The ERS Monograph is the quarterly book series from the ERS.

Each Monograph covers a specific area of respiratory medicine, providing in-depth reviews that give clinicians at all levels a concise, comprehensive guide to symptoms, diagnosis and treatment.


Exhaled Biomarkers

European Respiratory Society Monograph, Vol. 49. 2010
ISBN: 978-1-849840-05-7
DOI: 10.1183/1025448x.erm4910

Research within in the field of airway and lung inflammation has expanded tremendously during recent decades. Attempts are continuously being made to find novel methods to mirror and monitor inflammatory reactions related to airway disorders and dysfunction. The lungs are particularly well suited for this purpose as we have easy access to exhaled air and thereby a possibility to develop methods that measure compounds directly released from them.

As this area of interest is rather new this is the first issue of the European Respiratory Monograph to focus on inflammatory markers. As this field is rapidly expanding it was decided, after some initial discussions, to limit this Monograph to markers in exhaled air and to produce a comprehensive update of the entire field.


The Guest Editors

Eur Respir Monogr 2010; 49: v
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Preface
K. Larsson
Eur Respir Monogr 2010; 49: vi
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Introduction
I. Horvath, J. de Jongste
Eur Respir Monogr 2010; 49: vii
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Basic aspects of exhaled nitric oxide
K. Alving, A. Malinovschi
Eur Respir Monogr 2010; 49: 1-31
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Exhaled nitric oxide in asthma
D.E. Shaw, E. Wilson, I.D. Pavord
Eur Respir Monogr 2010; 49: 32-44
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Exhaled nitric oxide in respiratory diseases other than asthma
M.W.H. Pijnenburg
Eur Respir Monogr 2010; 49: 45-55
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Exhaled nitric oxide in infants: a marker of inflammation?
F. Singer, P. Latzin
Eur Respir Monogr 2010; 49: 56-70
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Nasal nitric oxide
M. Maniscalco, J.O. Lundberg
Eur Respir Monogr 2010; 49: 71-81
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Exhaled carbon monoxide: mechanisms and clinical applications
T. Dolinay, A.M.K. Choi, S.W. Ryter
Eur Respir Monogr 2010; 49: 82-95
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Methodological issues of sample collection and analysis of exhaled breath
A. Amann, W. Miekisch, J. Pleil, T. Risby, J. Schubert
Eur Respir Monogr 2010; 49: 96-114
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Interpretation of exhaled volatile organic compounds
G. Pennazza, M. Santonico, E. Martinelli, A. D'Amico, C. Di Natale
Eur Respir Monogr 2010; 49: 115-129
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Exhaled volatile organic compounds as biomarkers for respiratory diseases
P.J. Mazzone
Eur Respir Monogr 2010; 49: 130-139
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Exhaled volatile organic compounds in nonrespiratory diseases
M. Corradi, P. Gergelova, A. Mutti
Eur Respir Monogr 2010; 49: 140-151
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Exhaled breath condensate sample collection: standards and open issues
E. Dompeling, P.P.R. Rosias, Q. Jöbsis
Eur Respir Monogr 2010; 49: 152-161
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Exhaled breath condensate: hydrogen peroxide
S. Loukides, P. Bakakos, K. Kostikas
Eur Respir Monogr 2010; 49: 162-172
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Exhaled breath condensate pH
A. Bikov, B. Antus, G. Losonczy, I. Horvath
Eur Respir Monogr 2010; 49: 173-182
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Exhaled breath condensate: adenosine, ATP and other purines
Z. Lázár, G. Vass, É. Huszár, G. Losonczy, I. Horváth
Eur Respir Monogr 2010; 49: 183-195
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Exhaled breath condensate: 8-isoprostane and eicosanoids
P. Montuschi
Eur Respir Monogr 2010; 49: 196-206
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Exhaled breath condensate: nitric oxide-related compounds
L.E. Donnelly
Eur Respir Monogr 2010; 49: 207-216
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Interleukins and other proteins
C. Gessner, H. Wirtz
Eur Respir Monogr 2010; 49: 217-230
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Exhaled breath condensate: metabolomics
S. Carraro, G. Giordano, M. Stocchero, E. Baraldi
Eur Respir Monogr 2010; 49: 231-236
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Future perspectives on exhaled biomarkers
P.J. Barnes
Eur Respir Monogr 2010; 49: 237-246
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Summary and future developments
J.C. de Jongste, I. Horvath
Eur Respir Monogr 2010; 49: 247-249
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